Tide Motion Bioreactor

Tide motion pertains to the oscillation of culture medium into and out of the matrix vessel that intermittently exposures the cells to aeration and nutrition. The upward oscillation exposes the cells to nutrition, while the downward oscillation exposes the cells to aeration and at the same time washes away products and wastes. This gentle oscillation produces no air bubbles and causes very minimal shear stress, which are both detrimental to the cells.